1. A few weeks before arriving to your conference, take some time to read through the agenda and learn as much as you can about the speakers.
2. Make a list of speakers you want to meet and make short cheat sheets about them to bring up during your conversation.
3. Do not hesitate for a moment to approach them even if they happen to be top CEOs or Prime Ministers. Top secret - speakers are just as nervous or more so about how people perceive them. You will make them feel very happy if you approach them.
4. Have a clear goal in mind to achieve and go get it done! This is THE KEY. Without this goal, your conference can be the most painfully boring way of wasting time and money. Your goal may be as simple as getting business cards from as many people as you can and establishing contact through LinkedIn or other. Or you may be dealing with some issues and perhaps, they can help you with that. Or you may need their help in promoting your product and need to find out exactly what they can do for you.
5. Ask the organizers for a full list of registered attendees and request the organizers to set up meetings with specific people for you ahead of time, if possible.
6. Get as many business cards as you can and introduce yourself and your company. Even if you don't see value in doing it today, you never know how these people can help you in the future.
7. If you are not good at doing the above or don't have time, then send someone in your company who is good at it and ask them to summarize it for you and do the follow up.
8. Follow up with all the people you met with through email.
9. Connect with everyone you met with through LinkedIn.
10. Collect all presentation copies and keep them in your files.